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Original article

September 30, 2022


Comparative co-expression analysis of RNA-Seq transcriptome revealing key genes, miRNA and transcription factor in distinct metabolic pathways in diabetic nerve, eye, and kidney disease
Veeran kutty Subaida Shafna Asmy, Jeyakumar Natarajan
Genomics Inform. 2022;20(3):e26.

Diabetes and its related complications are associated with long term damage and failure of various organ systems. The microvascular complications of diabetes considered in this study are diabetic retinopathy, diabetic...

Original article

September 30, 2022


Pathogenesis and prognosis of primary oral squamous cell carcinoma based on microRNAs target genes: a systems biology approach
Amir Taherkhani, Shahab Shahmoradi Dehto, Shokoofeh Jamshidi, Setareh Shojaei
Genomics Inform. 2022;20(3):e27.

Oral squamous cell carcinoma (OSCC) is the most prevalent head and neck malignancy, with frequent cervical lymph-node metastasis, leading to a poor prognosis in OSCC patients. The present study aimed...

Original article

September 30, 2022


Whole-exome sequencing analysis in a case of primary congenital glaucoma due to the partial uniparental isodisomy
Parisima Ghaffarian Zavarzadeh, Morteza Bonyadi, Zahra Abedi
Genomics Inform. 2022;20(3):e28.

We described a clinical, laboratory, and genetic presentation of a pathogenic variant of the CYP1B1 gene through a report of a case of primary congenital glaucoma and a trio analysis...

Original article

September 30, 2022


The UGT1A9*22 genotype identifies a high-risk group for irinotecan toxicity among gastric cancer patients
Choong-kun Lee, Hong Jae Chon, Woo Sun Kwon, Hyo-Jeong Ban, Sang Cheol Kim, Hyunwook Kim, Hei-Cheul Jeung, Jimyung Chung, Sun Young Rha
Genomics Inform. 2022;20(3):e29.

Several studies have shown associations between irinotecan toxicity and UGT1A genetic variations in colorectal and lung cancer, but only limited data are available for gastric cancer patients. We evaluated the...

Original article

September 30, 2022


Two novel mutations in ALDH18A1 and SPG11 gene found by whole-exome sequencing in spastic paraplegia disease patients in Iran
Sajad Rafiee Komachali, Zakieh Siahpoosh, Mansoor Salehi
Genomics Inform. 2022;20(3):e30.

Hereditary spastic paraplegia is a not common inherited neurological disorder with heterogeneous clinical expressions. ALDH18A1 (located on 10q24.1) gene-related spastic paraplegias (SPG9A and SPG9B) are rare metabolic disorders caused by...

Original article

September 30, 2022


A systemic study on the vulnerability and fatality of prostate cancer patients towards COVID-19 through analysis of the TMPRSS2, CXCL10 and their co-expressed genes
Md. Thosif Raza, Shagufta Mizan
Genomics Inform. 2022;20(3):e31.

A pandemic of respiratory disease named coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is reported prostate cancer patients are...

Original article

September 30, 2022


Analysis of gene expression profiles to study malaria vaccine dose efficacy and immune response modulation
Supantha Dey, Harpreet Kaur, Mohit Mazumder, Elia Brodsky
Genomics Inform. 2022;20(3):e32.

Malaria is a life-threatening disease, and Africa is still one of the most affected endemic regions despite years of policy to limit infection and transmission rates. Further, studies into the...

Original article

September 30, 2022


Computer-aided drug design of Azadirachta indica compounds against nervous necrosis virus by targeting grouper heat shock cognate protein 70 (GHSC70): quantum mechanics calculations and molecular dynamic simulation approaches
Sk Injamamul Islam, Saloa Saloa, Sarower Mahfuj, Md Jakiul Islam, Moslema Jahan Mou
Genomics Inform. 2022;20(3):e33.

Nervous necrosis virus (NNV) is a deadly infectious disease that affects several fish species. It has been found that the NNV utilizes grouper heat shock cognate protein 70 (GHSC70) to...

Original article

September 30, 2022


The effect of missing levels of nesting in multilevel analysis
Seho Park, Yujin Chung
Genomics Inform. 2022;20(3):e34.

Multilevel analysis is an appropriate and powerful tool for analyzing hierarchical structure data widely applied from public health to genomic data. In practice, however, we may lose the information on...

Original article

September 30, 2022


Mining and analysis of microsatellites in human coronavirus genomes using the in-house built Java pipeline
Umang, P. K. Bharti, Akhtar Husai
Genomics Inform. 2022;20(3):e35.

Microsatellites or simple sequence repeats are motifs of 1 to 6 nucleotides in length present in both coding and non-coding regions of DNA. These are found widely distributed in the...

Application note

September 30, 2022


NBLAST: a graphical user interface-based two-way BLAST software with a dot plot viewer
Beom-Soon Choi, Seon Kang Choi, Nam-Soo Kim, Ik-Young Choi
Genomics Inform. 2022;20(3):e36.

BLAST, a basic bioinformatics tool for searching local sequence similarity, has been one of the most widely used bioinformatics programs since its introduction in 1990. Users generally use the web-based...

Letter to the editor

September 30, 2022


Viral culture, genome characterization, and mutation analysis of human influenza A virus
Rujittika Mungmunpuntipantip, Viroj Wiwanitkti
Genomics Inform. 2022;20(3):e37.
Current Issue
Volume 20(3); Sep 2022
Editor’s introduction to this issue (G&I 20:3, 2022)
Taesung Park
Genomics Inform. 2022;20(3):e25.

Editorial

September 30, 2022
Comparative co-expression analysis of RNA-Seq transcriptome revealing key genes, miRNA and transcription factor in distinct metabolic pathways in diabetic nerve, eye, and kidney disease
Veeran kutty Subaida Shafna Asmy, Jeyakumar Natarajan
Genomics Inform. 2022;20(3):e26.

Original article

September 30, 2022
Pathogenesis and prognosis of primary oral squamous cell carcinoma based on microRNAs target genes: a systems biology approach
Amir Taherkhani, Shahab Shahmoradi Dehto, Shokoofeh Jamshidi, Setareh Shojaei
Genomics Inform. 2022;20(3):e27.

Original article

September 30, 2022
Whole-exome sequencing analysis in a case of primary congenital glaucoma due to the partial uniparental isodisomy
Parisima Ghaffarian Zavarzadeh, Morteza Bonyadi, Zahra Abedi
Genomics Inform. 2022;20(3):e28.

Original article

September 30, 2022
The UGT1A9*22 genotype identifies a high-risk group for irinotecan toxicity among gastric cancer patients
Choong-kun Lee, Hong Jae Chon, Woo Sun Kwon, Hyo-Jeong Ban, Sang Cheol Kim, Hyunwook Kim, Hei-Cheul Jeung, Jimyung Chung, Sun Young Rha
Genomics Inform. 2022;20(3):e29.

Original article

September 30, 2022
Two novel mutations in ALDH18A1 and SPG11 gene found by whole-exome sequencing in spastic paraplegia disease patients in Iran
Sajad Rafiee Komachali, Zakieh Siahpoosh, Mansoor Salehi
Genomics Inform. 2022;20(3):e30.

Original article

September 30, 2022
A systemic study on the vulnerability and fatality of prostate cancer patients towards COVID-19 through analysis of the TMPRSS2, CXCL10 and their co-expressed genes
Md. Thosif Raza, Shagufta Mizan
Genomics Inform. 2022;20(3):e31.

Original article

September 30, 2022
Analysis of gene expression profiles to study malaria vaccine dose efficacy and immune response modulation
Supantha Dey, Harpreet Kaur, Mohit Mazumder, Elia Brodsky
Genomics Inform. 2022;20(3):e32.

Original article

September 30, 2022
Computer-aided drug design of Azadirachta indica compounds against nervous necrosis virus by targeting grouper heat shock cognate protein 70 (GHSC70): quantum mechanics calculations and molecular dynamic simulation approaches
Sk Injamamul Islam, Saloa Saloa, Sarower Mahfuj, Md Jakiul Islam, Moslema Jahan Mou
Genomics Inform. 2022;20(3):e33.

Original article

September 30, 2022
The effect of missing levels of nesting in multilevel analysis
Seho Park, Yujin Chung
Genomics Inform. 2022;20(3):e34.

Original article

September 30, 2022
Mining and analysis of microsatellites in human coronavirus genomes using the in-house built Java pipeline
Umang, P. K. Bharti, Akhtar Husai
Genomics Inform. 2022;20(3):e35.

Original article

September 30, 2022
NBLAST: a graphical user interface-based two-way BLAST software with a dot plot viewer
Beom-Soon Choi, Seon Kang Choi, Nam-Soo Kim, Ik-Young Choi
Genomics Inform. 2022;20(3):e36.

Application note

September 30, 2022
Viral culture, genome characterization, and mutation analysis of human influenza A virus
Rujittika Mungmunpuntipantip, Viroj Wiwanitkti
Genomics Inform. 2022;20(3):e37.

Letter to the editor

September 30, 2022

View More

Most View Most Cited
Whole-exome sequencing analysis in a case of primary congenital glaucoma due to the partial uniparental isodisomy Parisima Ghaffarian Zavarzadeh, Morteza Bonyadi, Zahra Abedi Genomics Inform. 2022;20(3):e28. Subrata K. Biswas, Sonchita R. Mudi Genomics Inform. 2020;18(4):e44. Cited By 20
A systemic study on the vulnerability and fatality of prostate cancer patients towards COVID-19 through analysis of the TMPRSS2, CXCL10 and their co-expressed genes Md. Thosif Raza, Shagufta Mizan Genomics Inform. 2022;20(3):e31. Karl R. Franke, Erin L. Crowgey Genomics Inform. 2020;18(1):e10. Cited By 12
The UGT1A9*22 genotype identifies a high-risk group for irinotecan toxicity among gastric cancer patients Choong-kun Lee, Hong Jae Chon, Woo Sun Kwon, Hyo-Jeong Ban, Sang Cheol Kim, Hyunwook Kim, Hei-Cheul Jeung, Jimyung Chung, Sun Young Rha Genomics Inform. 2022;20(3):e29. Ramya Tekumalla, Juan M. Banda Genomics Inform. 2020;18(2):e16. Cited By 11
The effect of missing levels of nesting in multilevel analysis Seho Park, Yujin Chung Genomics Inform. 2022;20(3):e34. Danbi Seo, Dain Kim, Yeonsoo Chae, Wanyeon Kim Genomics Inform. 2020;18(4):e36. Cited By 11
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