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Genomics Inform > Volume 3(2); 2005 > Article
BioCovi: A Visualization Service for Comparative Genomics Analysis.
Jungsul Lee, Daeui Park, Jong Bhak
1Department of BioSystems, KAIST, Daejeon 305-701, Korea.
2Object Interaction Technologies Inc., Daejeon 305-701, Korea.
3NGIC, KRIBB, Daejeon 305-806, Korea.
Visualization of the homology information is an important method to analyze the evolutionary and functional meanings of genes. With a database containing model genomes of Homo sapiens, Mus muculus, and Rattus norvegicus, we constructed a web-based comparative analysis tool, BioCovi, to visualize the homology information of mammalian sequences on a very large scale. The user interface has several features: it marks regions whose identity is greater than that specified, it shows or hides gaps from the result of global sequence alignment, and it inverts the graph when total identity is higher than the threshold specified.
Keywords: comparative genomics; visualization
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