Editor's Introduction to This Issue (G&I 15:2, 2017)

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Genomics Inform. 2017;15(2):55-55
Publication date (electronic) : 2017 June 15
doi : https://doi.org/10.5808/GI.2017.15.2.55
IRCGP, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Corresponding author: Tel: +82-2-2258-7343, Fax: +82-2-537-0572, yejun@catholic.ac.kr

In this issue, Dr. Jong-Il Kim's group (Seoul National University, Korea) reports gene expression profile data in human dermal fibroblasts treated with COX inhibitors. Some COX2-selective inhibitors inhibit cellular senescence, but other COX2-selective inhibitors and COX2 nonselective inhibitors accelerate senescence and aging. The authors tried to figure out the underlying mechanisms by which COX inhibitors modulate senescence in the skin. Dr. Yeun-Jun Chung's group (The Catholic University of Korea) suggests that a variant in RUNX3 is associated with the risk of ankylosing spondylitis in Koreans. Dr. Mana Oloomi's group (Pasteur Institute of Iran) demonstrates a sporadic phylogenic pattern in cytolethal distending toxin-producing Escherichia coli strains.

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