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Genomics Inform > Volume 2(2); 2004 > Article
HapAnalyzer: Minimum Haplotype Analysis System for Association Studies.
Ho Youl Jung, Jung Sun Park, Yun Ju Park, Young Jin Kim, Kuchan Kimm, In Song Koh
Division of Epidemiology and Bioinformatics, National Genome Research Institute, National Institute of Health, 5 Nokbun-dong, Eunpyeng-gu, Seoul, 122-701, Korea. insong@nih.go.kr
Abstract
SUMMARY: HapAnalyzer is an analysis system that provides minimum analysis methods for the SNP-based association studies. It consists of Hardy-Weinberg equilibrium (HWE) test, linkage disequilibrium (LD) computation, haplotype reconstruction, and SNP (or haplotype)-phenotype association assessment. It is well suited to a case-control association study for the unrelated population.
Keywords: SNP; haplotype; haplotype block; disease association
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