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Elucidating molecular mechanisms of acquired resistance to BRAF inhibitors in melanoma using a microfluidic device and deep sequencing |
Jiyeon Han, Yeonjoo Jung, Yukyung Jun, Sungsu Park, Sanghyuk Lee |
Genomics Inform. 2021;19(1):e2 Published online March 15, 2021 DOI: https://doi.org/10.5808/gi.20074 |
Elucidating molecular mechanisms of acquired resistance to BRAF inhibitors in melanoma using a microfluidic device and deep sequencing Clinical Implications of Acquired BRAF Inhibitors Resistance in Melanoma Detecting Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma Adaptive Responses as Mechanisms of Resistance to BRAF Inhibitors in Melanoma Low inducible expression of p21Cip1 confers resistance to paclitaxel in BRAF mutant melanoma cells with acquired resistance to BRAF inhibitor Molecular Mechanisms of Acquired Resistance to Kinase Inhibitors Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma The path of least resistance: enhancing the effectiveness of BRAF inhibitors Integrative RNAseq and target panel sequencing reveals common and distinct innate and adaptive resistance mechanisms to BRAF inhibitors |