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Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis |
Satish Kumar, Lingaraja Jena, Sneha Galande, Sangeeta Daf, Kanchan Mohod, Ashok K. Varma |
Genomics Inform. 2014;12(2):64-70. Published online June 30, 2014 DOI: https://doi.org/10.5808/GI.2014.12.2.64 |
Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis Molecular analysis of the interaction between HPV type 16 E6 and human E6-associated protein Specific recognition of four-way DNA junctions by the C-terminal zinc-binding domain of HPV oncoprotein E6 HPV-18 E6 Oncoprotein and Its Spliced Isoform E6*I Regulate the Wnt/β-Catenin Cell Signaling Pathway through the TCF-4 Transcriptional Factor 721. Enhanced Antitumor Cellular Immunity Induced by a Novel HPV-16 DNA Vaccine Encoding a E6/E7 Fusion Consensus Protein The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors The high-risk HPV E6 oncoprotein preferentially targets phosphorylated nuclear forms of hDlg Subcellular localization and quantitation of the human papillomavirus type 16 E6 oncoprotein through immunocytochemistry detection Low-Cost Molecular Biomarker HPV-16/18 E6 Oncoprotein Expression in Cervical Intraepithelial Neoplasia (CIN) and Cervical Cancer with Its Relation with Severity of Neoplastic State |